Dr. Mario: Miracle Cure doesn't offer too many improvements outside of the Miracle Cures and graphical updates, but that's kind of expected with certain puzzle games.  The game still provides a solid Dr. Mario experience with the Dr. Luigi and Virus Buster game modes thrown in and the addition of the Miracle Cures shakes things up a bit, both online and off, but the lack of an overall high score for your game session seems like a step backwards for a standard puzzle game.  While not perfect, if you're looking for some Dr. Mario on the go, Miracle Cure is still worth a shot.